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Visual side effects probably problems with erection as a consequence of off-target inhibition of PDE6, which is structurally similar to PDE5 and is involved in regulating phototransduction, the authors say. Visual effects of PDE5 inhibitors are typically mild and transient. However, visual complications of long-term use have been suggested, the authors add.

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The pharmaceutically acceptable salts include salts derived from pharmaceutically acceptable acids or bases. The pharmaceutically acceptable salts in the present invention mean any organic or inorganic addition salt which has a relatively soft erection and innocuous effective action on the patient and in which side effects due to the salt do not impair the beneficial efficacy of weak erection pharmacologically active ingredient do. Examples of pharmaceutically acceptable salts of tadalafil include hydrobromic acid salts, phosphates, sulfates, hydrochlorides, malates, fumarates, lactates, tartrates, citrates, besylates, camsylates and gluconates.

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If you get these side effects, keep taking the medicine, but tell a doctor or pharmacist if they bother you or do not go away: headaches feeling sick nausea red or flushed face indigestion stuffy nose muscle aches Serious side effects Serious side effects are rare and happen in less than 1 in 1, people. Stop taking tadalafil and call a doctor straight away if you get: chest pains - if this happens during or after sex, get into a semi-sitting position and try to relax remember do not use nitrates for chest pain while taking tadalafil prolonged and sometimes painful Sildenafil 100mg tabs - if you have an erection erection lasts for more than 4 hours, contact a doctor immediately a sudden problem with your eyesight or hearing a serious skin reaction - symptoms may include red raised patches on your skin or red spots hivesa swollen face and swelling around the eyes seizures or fits Serious allergic reaction In rare cases, tadalafil can cause a serious allergic reaction anaphylaxis.

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